Vial Containment Solutions

Cell and Gene Therapy

By Abbey Hisler

九月 28, 2020

Gene therapies are developed by modifying a person’s genes and are often targeted to treat complex and chronic diseases. Due to advancements in science and research, gene therapy is positioned to transform treatment options for patients who are living with these incurable diseases. There is a growing pipeline of gene therapies globally, with 352 global trials underway at the end of 2019, up 12% from 2017.1.

Cell and Gene Therapy

By Page McAndrew, PhD

九月 04, 2020

Gene therapies are stored and shipped at ultra-low temperature (approximately -80oC, either in a refrigerator or on dry ice). This provides a challenge to the primary package systems in maintaining container closure integrity (CCI), especially systems comprising glass vials and elastomer stoppers. These materials have different coefficients of thermal expansion. Upon cooling from room temperature to ultra-low temperature, they contract at different rates; this may lead to gaps and CCI loss.

Patient receiving medication from doctor

By Victoria Morgan

八月 19, 2020

Regulatory agencies are driving the pharmaceutical industry to continuously improve the quality of drug products, but what is the reality for a drug developer who is expected to make parenteral preparations “practically free from particles”? Expectations of packaging are changing fast but how well prepared is the packaging to meet these needs?


By Mary Tan

八月 03, 2020

A good elastomer stopper for a vial container system needs to have the right properties. These properties are largely determined by the elastomer formulation, which comprises the base elastomer, fillers, plasticizers, and curing agents. The interplay among these components is crucial, as they determine performance. For example, hardness is affected by filler type and level, as well as by curing agent and level. West understands these issues, and therefore is able to develop formulations to offer maximum performance. An example is the formulation 4040/40, which was designed according to quality-by-design (QbD) principles.

By Your Side for Service

By Carol Mooney

七月 15, 2020

West is pleased to announce that we’ve recently expanded our Online Store offerings to include a 20mm NovaPure® Ready Pack™ lyophilization stopper, adaptiQ® vials from SCHOTT and Ready Pack™ Flip-Off® CCS (Clean, Certified, Sterilized) seals. West’s Online Store is a one-stop solution for access to small quantities of some of West’s highest quality products, in stock and available ready-to-use in convenient small packs. Depending on their product needs, shoppers can now purchase a complete vial containment system with the option of selecting either Daikyo Crystal Zenith® or adaptiQ glass vials.

Capped Vials

By Melanie Prudom

六月 04, 2020

“Choosing the Right Components for Container Closure Systems,” the second part of our “How to Qualify Container Closure Systems” series, was recently published in the International Journal of Pharmaceutical Compounding. The article addresses ways in which packaging component selection is critical to ensuring that the closure container system will protect and maintain compounded drug quality.1

色姑娘精品六 芦溪县| 博湖县| 大余县| 祁门县| 龙里县| 英山县| 那坡县| 宣化县| 连平县| 寻甸| 古田县| 岚皋县| 界首市| 神农架林区| 上思县| 和平区| 卢氏县| 大邑县| 康马县| 屏东县| 香河县| 姜堰市| 铁岭市| 卢湾区| 盐城市| 抚顺市| 岳西县| 柏乡县| 汉中市| 沁阳市| 兰西县| 美姑县| 古田县| 嘉峪关市| 诏安县| 定州市| 莱西市| 阿合奇县| 新乐市| 恩施市| 玛纳斯县| http:// http:// http://